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This late response leads to prolonged hypoxia and correlates with poor outcome, due to resulting refractory vasodilatory shock, among other factors

While current clinical candidates focus primarily on selective MC4R agonism for the limited treatment of genetic and hypothalamic obesity, 710GO appears to be the only current developmental program poised to address general obesity as a monotherapy

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For example, Cacciottola et al (16) provided a comprehensive review on the aberrant ROS metabolism observed in patients with endometriosis and the contributory role of ROS in disease progression